Assessment of perfusion in MRI

Perfusion imaging has been subject matter for different projects.
We developed an algorithm for automatic and quantitative analysis of perfusion MRI with esogenic contrast medium.

Related publications

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• G. Tarroni, C. Corsi, P.F. Antkowiak, F. Veronesi, C.M. Kramer, F.H. Epstein, J. Walter, C. Lamberti, R. M. Lang, V. Mor-Avi, A.R. Patel, Myocardial perfusion: near-automated evaluation from contrast-enhanced MR images obtained at rest and during vasodilator stress, Radiology, 265:576-583, 2012.
• G. Tarroni, A.R. Patel, C. Yodwut, R.M. Lang, C. Lamberti, V. Mor-Avi, C. Corsi, Automated Tracking of Deformable Objects Based on Non-Rigid Registration of Cardiac Images, Computing in Cardiology 2012 (Krakow, Poland, September 9-12, 2012), edited by Alan Murray, IEEE Press, Vol. 39:693-696, 2012.
• G. Tarroni, A.R. Patel, F. Veronesi, J. Walter, C. Lamberti, R.M. Lang, V. Mor-Avi, C. Corsi, MRI-Based Quantification of Myocardial Perfusion at Rest and Stress Using Automated Frame-by-Frame Segmentation and Non-Rigid Registration, Computers in Cardiology 2010 (Belfast, IR, September 26-29, 2010), edited by Alan Murray, IEEE Press, Vol. 37:1-4.
• G. Tarroni, C. Corsi, F. Veronesi, J. Walter, C. Lamberti, R.M. Lang, V. Mor-Avi, A.R. Patel, Automated Quantification of Myocardial Perfusion Based on Segmentation and Non-Rigid Registration of Contrast-Enhanced Cardiac Magnetic Resonance Images, 2011 SCMR/EuroCMR Joint Scientific Sessions, 3-6 February 2011 - Nice, France, Journal of Cardiovascular Magnetic Resonance 2011, 13(1):P91.
• G. Tarroni, A.R. Patel, P.F. Antkoviak, F.H. Epstein, C.M. Kramer, C. Lamberti, R.M. Lang, V. Mor-Avi, C. Corsi, Automated frame-by-frame segmentation and non-rigid registration of MRI myocardial perfusion data at rest and stress, Int J CARS (2011) 6 (Suppl 1):S25;

SurgAid project

Severe mitrial valve (MV) regurgitation associated to degenerative MV prolapse is one of the most common valvular pathologies in the industrialized countries, and it’s characterized by high morbidity and mortality. MV repair with annuloplasty is currently the primary surgical solution for this pathology. However, some clinical questions related to this approach are still unsolved. The SurgAid project, co-funded by the Italian Ministry of Research under the PRIN2007 - Young Researchers program (www.surgaid.org), aims to overcome these limitations, by providing new image processing techniques in order to extract from E3D images novel quantitative information about MV annulus regional geometry and dynamics, papillary muscles position, LV global and regional shape. This project is both interdisciplinary (involving both electronic and mechanical biomedical engineering competences) and multi-disciplinary (in collaboration with heart surgeons, cardiologists and cardiac imaging technicians of the partner clinical institutions).

Related publications

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• E.G. Caiani, L. Fusini, F. Veronesi, G. Tamborini, F. Maffessanti, P. Gripari, C. Corsi, M. Naliato, M. Zanobini, F. Alamanni, M. Pepi, Quantification of Mitral Annulus Dynamical Morphology in Patients with Mitral Valve Prolapse undergoing Repair and Annuloplasty during a 6-months Follow-up, European Journal of Echocardiography, 12(5): 375-383, 2011.
• F. Veronesi, C. Corsi, L. Sugeng, V. Mor-Avi, E.G. Caiani, L. Weinert, C. Lamberti, R.M. Lang. A Study of Functional Anatomy of Aortic-Mitral Valve Coupling Using 3D Matrix Transesophageal Echocardiography, Circulation: Cardiovascular Imaging vol. 2(1):24-31, 2009.
• F. Veronesi, E.C. Caiani, C. Corsi, C. Lamberti, Comparison of 2D and 3D echocardiographic measurement of Mitral-Aortic Angle, Computing in Cardiology 2013 (Zaragoza, Spain September 22-25, 2013), edited by Alan Murray, IEEE Press, Vol. 40:253-256, 2013. ID 400287
• L. Fusini, F. Veronesi, C. Corsi, P. Gripari, F. Maffessanti, F. Alamanni, M. Zanobini, M. Naliato, G. Tamborini, M. Pepi, E.G. Caiani, Quantitative Assessment of the Effects of Annuloplasty on Mitral Annulus Dynamic Geometry Using Real-Time 3D Echocardiography, Computers in Cardiology 2010 (Belfast, IR, September 26-29, 2010), edited by Alan Murray, IEEE Press, Vol. 37:393:396.
• F. Veronesi, C. Corsi, V. Mor-Avi, L. Sugeng, L. Wienert, R.M. Lang, C. Lamberti, Quantification of aortic valve stenosis using transesophageal real-time 3D echocardiography, Computers in Cardiology 2009 (Park City, UT, USA, September 13-16, 2009), edited by Alan Murray, IEEE Press, Vol. 36:37-40. Presentation
• F. Veronesi, C. Corsi, V. Mor-Avi, L. Sugeng, E.G. Caiani, L. Weinert, C. Lamberti, R.M. Lang. Semi-Automatic Detection and Tracking of Mitral and Aortic Annuli from Real– Time 3D Transesophageal Echocardiographic Images, Computers in Cardiology 2008 (Bologna, Italy, September 14-17, 2008), edited by Alan Murray, IEEE Press, Vol. 35:33-36.
• F. Veronesi, D. Muraru, K. Addetia, C. Corsi, C. Lamberti, R.M. Lang, V. Mor-Avi, L.P. Badano Dynamic three-dimensional evaluation of tricuspid valve morphology and function in patients with pulmonary hypertension, EuroEcho-Imaging 2013 (Istanbul – Turkey, 11 - 14 December 2013)
• F. Veronesi, D. Muraru, K. Addetia, C. Corsi, C. Lamberti, R.M. Lang, V. Mor-Avi, L.P. Badano, A novel software tool to semi-automatically characterize tricuspid valve function and shape using trans-thoracic 3d echocardiography, EuroEcho-Imaging 2013 (Istanbul – Turkey, 11 - 14 December 2013)
• F. Veronesi,. C. Corsi, C. Lamberti, R.M. Lang, V. Mor-Avi. Estimates of mitral-aortic angle measurement errors in 2D compared to 3D echocardiography, EuroEcho-Imaging 2013 (Istanbul – Turkey, 11 - 14 December 2013). Poster